Awesome Bio Agent Skills

A curated collection of AI agent skills for biomedical research, covering genomics, proteomics, single-cell analysis, clinical AI, and protein design.

Now tracking NVIDIA BioNeMo Agent Toolkit, Claude Science built-in skills, and the emerging ecosystem of agent-callable tools for life sciences.

1,722 deduplicated skills from 22 open-source repositories, organized into 16 categories. Each skill is a self-contained SKILL.md folder compatible with Claude-based agent frameworks (OpenClaw, NanoClaw, Biomni).

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About BioTender

This project is created and maintained by BioTender.

BioTender is a Chinese AI-for-Biology intelligence and media platform covering protein design, structure prediction, virtual cells, AI drug discovery, biological foundation models, scientific agents, AI4Bio startups, and frontier research.

• Website: https://www.biotender.online/
• About: https://www.biotender.online/about/
• Scholar Program: https://www.biotender.online/scholar-program.html

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Contents

• Genomics
• Proteomics
• Single-Cell Analysis
• Biology and AI
• Clinical and Medical
• Transcriptomics
• Database Query
• Multi-Omics Integration
• Bioinformatics Utilities
• Visualization
• Workflow Orchestration
• Epigenomics
• Pathway Analysis
• Metagenomics
• Protein Design
• NVIDIA BioNeMo Skills
• Claude Science Skills
• Sources

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Genomics

526 skills — WGS/WES analysis, variant annotation, GWAS, CNV, structural variants, haplotype phasing, genome assembly.

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Proteomics

167 skills — mass spectrometry analysis, structure prediction, protein design, binding affinity optimization.

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Single-Cell Analysis

144 skills — preprocessing, clustering, cell type annotation, trajectory inference, cell communication, multimodal integration.

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Biology and AI

236 skills — medical AI, clinical decision support, drug discovery, general biological tools.

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Clinical and Medical

152 skills — EHR analysis, clinical trial design, drug interactions, precision medicine, adverse event detection.

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Transcriptomics

97 skills — RNA-seq full pipeline, differential expression, alternative splicing, lncRNA, small RNA.

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Database Query

63 skills — UniProt, PDB, KEGG, Reactome, GEO, ClinVar, Ensembl, STRING.

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Multi-Omics Integration

69 skills — MOFA, DIABLO, single-cell multimodal, spatial transcriptomics.

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Bioinformatics Utilities

86 skills — sequence analysis, BLAST, tool chains, pipeline management.

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Visualization

48 skills — volcano plots, heatmaps, PCA/UMAP, interactive charts.

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Workflow Orchestration

38 skills — Snakemake, Nextflow, CWL, WDL.

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Epigenomics

19 skills — ChIP-seq, ATAC-seq, DNA methylation, Hi-C, chromatin state.

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Pathway Analysis

15 skills — KEGG, Reactome, GO, GSEA.

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Metagenomics

9 skills — 16S/ITS amplicon, Kraken2, MetaPhlAn, QIIME2.

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Protein Design

7 skills — RFDiffusion, ProteinMPNN, Boltz, Chai, LigandMPNN.

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NVIDIA BioNeMo Skills

17 skills — Official NVIDIA BioNeMo NIM API skills for protein structure prediction, molecular generation, and genomics.

Source: NVIDIA-BioNeMo/bionemo-agent-toolkit · License: Apache-2.0 (code) / CC-BY-4.0 (skills)

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Claude Science Skills

29 skills — Reverse-engineered Claude Science built-in skills covering biomolecular modeling, genomics, single-cell analysis, literature synthesis, and scientific compute workflows.

Source: JimLiu/science-skills · License: Apache-2.0 · Reverse-engineered from Claude Science · Synced: fb309c3 (2026-07-01)

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Sources

This collection aggregates and deduplicates skills from the following open-source repositories:

Skill Format

Each skill is a self-contained folder with a SKILL.md file defining domain knowledge, tool usage, and expected outputs. Compatible with any Claude-based agent framework supporting the SKILL.md convention.

skills/
└── /
    └── /
        ├── SKILL.md          # Skill definition (required)
        └── ...               # Supporting files

Quick install:

git clone https://github.com/BioTender-max/awesome-bio-agent-skills.git
cp -r awesome-bio-agent-skills/skills/* /path/to/your/agent/skills/

A machine-readable index of all 1,693 skills is available in bioskill_index_v3.csv.

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